EFFICACY AND SAFETY OF LURASIDONE IN SCHIZOPHRENIA (LITERATURE REVIEW)

Abstract

The article discusses the most important features of a novel atypical antipsychotic agent lurasidone in terms of the recent treatment approach to schizophrenia patietns, such as its antirelapse and antidepressant activity, a favorable safety profile, as well as a procognitive effect. It includes core randomized placebo> and active comparator controlled clinical trials, which demonstrated a convincing efficacy of lurasidone for different symptom domains of schizophrenia compared to placebo and comparability with the efficacy of other atypical antipsychotics. A number of practical recommendations for use of lurasidone are given.