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No. 4 (2022)

ТЕРАПИЯ ПСИХИЧЕСКИХ РАССТРОЙСТВ В ПОЗДНЕМ ВОЗРАСТЕ

The Use of Trazodone in neuropsychiatric Disorders in the Elderly

https://doi.org/10.21265/PSYPH.2022.60.29.006%20

Published 2022-12-31

  • A.Yu. Nikitina
    • ,
  • O.S. Levin

A.Yu. Nikitina
Russian Medical Academy of Postgraduate Education

O.S. Levin
Russian Medical Academy of Postgraduate Education

Abstract

Trazodone is antidepressant with unique properties that, in addition to depression therapy, can be used to treat anxiety disorders, insomnia, chronic pain syndromes, somatoform disorders, and is also the drug of choice for correcting behavioral and psychological symptoms of dementia. Prolonged Trazodone usage has a positive effect on cognitive functions primarily due to the normalization of sleep and a decrease in the severity of affective disorders. In addition, itъis currently assumed that trazodone may have a neuroprotective effect, affecting the pathogenetic mechanisms of neurodegeneration. The article discusses the mechanism of action of trazodone, as well as the possibility of its use in the elderly.

Keywords

trazodone, dementia, insomnia, depression, aggression, neurodegenerative diseases

PDF (Русский)

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