The problems of aripiprazole therapy drug tolerance (endocrinological aspect)
Abstract
Introduced review has dedicated to one of the psychopharmacological significant problems – endocrinological aspects of drug tolerance by second$generation antipsychotics (SGA). Below presents the data of comparative studies by influence of separate antipsychoticscompared toaripiprazole on levels of serum prolactin, high$ and low$density lipoproteins (HDL and LDL), glucose and mass of a body change in the patients with mental illness. There were showed the aripiprazole preferences in respect of hyperprolactinemia (HP) and metabolic disorders.
Keywords
aripiprazole, hyperprolactinemia, weight gain, high- and low-density lipoproteins (HDL and LDL), glucose level