Drug Interactions drugs in antipsychotic therapy schizophrenia: right and risky drug combinations

Abstract

The combination of several psychotropic drugs without taking into account drug interactions can adversely affect the quality of life and lead to an increased risk of adverse effects in the treatment of patients with schizophrenia. This brief review provides data on the pharmacokinetic and pharmacodynamic interactions of the drugs most commonly used in the treatment of this disease, and indicates the basic principles for accounting for these interactions.