The Effect of the Antipsychotic Cariprazine on the Cognitive Functioning of Patients with Schizophrenia: Review of Evidence-Based Studies of the Drug

Abstract

Cognitive disorders are defined as one of the key groups of disorders in schizophrenia, they occupy an important place in the structure of the schizophrenic process and have a major impact on the outcome of the disease, indicators of social and labor adaptation of patients. This review article reviews and compares data from a number of clinical studies and reviews of publications on the neurochemical causes of the formation of cognitive disorders in schizophrenia. The existence of a relationship between the degree of severity of negative and cognitive disorders is substantiated. According to domestic and foreign sources, the mechanisms of influence of the new atypical antipsychotic kariprazine on the cognitive functioning of patients with schizophrenia are given. Data analysis demonstrated the ability of cariprazine to have a positive effect on cognitive functions.