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No. 4 (2018)

NEW MEDICINES

Orally Disintegrating Tablets: Potentials in Psychiatry

https://doi.org/10.21265/PSYPH.2018.47.21792

Published 2018-12-30

  • E.V. Oleneva
    • ,
  • P.V. Ryvkin
    • ,
  • M.Ya. Ladyzhensky
    • ,
  • S.N. Mosolov

E.V. Oleneva
Moscow Research Institute of Psychiatry - Branch of the V.P. Serbsky National Medical Research Center of Psychiatry and Narcology of the Ministry of Health of the Russian Federation

P.V. Ryvkin
Federal Medical Research Center for Psychiatry and Narcology by the name of V.P. Serbsky Minzdrava RF

M.Ya. Ladyzhensky
Federal Medical Research Center for Psychiatry and Narcology by the name of V.P. Serbsky Minzdrava RF

S.N. Mosolov
Federal Medical Research Center for Psychiatry and Narcology by the name of V.P. Serbsky Minzdrava RF

Abstract

The review examines the main ideas about the bioavailability and bioequivalence of drugs, as well as various aspects related to the practical use of orally disintegratable forms of psychotropic
drugs, their disadvantages, advantages, features of pharmacokinetics and biotransformation. The issues of the impact of this method of administration of drugs on compliance and the
effectiveness of therapy in general, using the results of clinical studies and statistical modeling, are highlighted.

Keywords

orally disintegrating tablet, bioequivalence, bioavailability, compliance

PDF (Русский)

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